This review highlights emerging pharmacological and interventional alternatives to warfarin for stroke prevention in atrial fibrillation, emphasizing left atrial appendage occlusion for patients contraindicated for oral anticoagulation.
May support LAAO or ablation in anticoagulation-intolerant AF; leaves open need for head-to-head RCTs.
Fibrilace sĂnĂ je nejÄastÄjĹĄĂ supraventrikulĂĄrnĂ arytmiĂ. Na zĂĄkladÄ tvorby sĂĹovĂ˝ch trombĹŻ, zejmĂŠna v ouĹĄku levĂŠ sĂnÄ, je tato arytmie spojena s vĂ˝raznÄ zvýťenĂ˝m rizikem vzniku cĂŠvnĂ mozkovĂŠ pĹĂhody. V tomto ÄlĂĄnku se zamÄĹĂme na rĹŻznĂŠ farmakologickĂŠ, chirurgickĂŠ a katetrizaÄnĂ metody prevence vzniku cĂŠvnĂ mozkovĂŠ pĹĂhody u pacientĹŻ s fibrilacĂ sĂnĂ.
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Táborský et al. (2008) studied this question.
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