Key result
The concept of a constant RC-time in the pulmonary circulation is challenged by emerging evidence, as standard equations may overestimate true resistance and compliance in pulmonary hypertension.
The assumption of a constant RC-time in the pulmonary circulation is challenged, highlighting the need to reevaluate standard equations for PVR and compliance in pulmonary hypertension.
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Standard RC-time equations may overestimate PVR and compliance in PH; leaves open need for prospective validation before clinical adoption.
Chemla et al. (2015) conducted a review in Pulmonary hypertension. The concept of a constant RC-time in the pulmonary circulation is challenged by emerging evidence, as standard equations may overestimate true resistance and compliance in pulmonary hypertension.
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