Why the study?
Does acute occlusion of a coronary artery in a previously normal heart lead to the development of a collateral circulation, and how long does it take to establish?
Does acute occlusion of a coronary artery in a previously normal heart lead to the development of a collateral circulation, and how long does it take to establish?
This experimental study aims to determine if and how quickly acute coronary occlusion stimulates the development of collateral circulation in a previously normal heart.
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Animal data on acute collateral recruitment leave open translation to human coronary occlusion timelines and management.
Paul et al. (1957) studied this question.
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