Key result
Complex analysis of T-wave parameters and RT interval variability from 24-hour ECG recordings can identify patients at increased risk of sudden death.
Why the study?
Does the evaluation of ventricular repolarization parameters from surface ECG correlate with myocardial electrical instability in patients with ventricular arrhythmias?
Observational (n=91)
Does the evaluation of ventricular repolarization parameters from surface ECG correlate with myocardial electrical instability in patients with ventricular arrhythmias?
Analysis of T-wave parameters and RT interval variability from 24-hour ECG recordings may help identify patients with ventricular arrhythmias who are at increased risk of sudden cardiac death.
May aid risk stratification in ventricular arrhythmia patients; leaves open prospective validation of repolarization metrics.
In order to reveal the possible correlation between the level of myocardial electrical instability assessed at Holter monitoring and certain ECG parameters characterizing ventricular repolarization 24-hours ECG recordings were analyzed in 91 patients with different grades of ventricular arrhythmias. The following parameters were calculated: RT-interval (RT) duration and variability, RT apex interval (RTa) duration and variability, areas of the first and second half of T-wave (S1, S2) and maximal rise and fall slopes of T-wave (k1, k2). An original signal processing algorithm for ECG was developed for that purpose. The results of the study suggest that complex analysis of certain T-wave parameters, as well as RT interval variability can be a useful tool for identification of patients at increased risk of sudden death.
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Lass et al. (2005) conducted an observational in Ventricular arrhythmias (n=91). Ventricular repolarization ECG parameters was evaluated on Correlation between myocardial electrical instability and ECG parameters. Complex analysis of T-wave parameters and RT interval variability from 24-hour ECG recordings can identify patients at increased risk of sudden death.
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