What does this research mean for the field?

Advanced ECG-derived measures of repolarization abnormality, specifically relative T wave residuum (TWR-rel) and total cosine R-to-T (TCRT), are independent predictors of appropriate therapy for ventricular arrhythmias in patients with implantable cardioverter-defibrillators. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 13, 2016Annals of Noninvasive ElectrocardiologyOpen Access

Analysis of ECG Measures of Cardiac Repolarization in Relation to Arrhythmic Events in an Implantable Cardioverter Defibrillator Population

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Why the study?

Do ECG-derived measures of cardiac repolarization predict appropriate therapy in patients receiving new ICD implants?

Structured PICO

Do ECG-derived measures of cardiac repolarization predict appropriate therapy in patients receiving new ICD implants?

Population

150 patients receiving new implantable cardioverter defibrillator (ICD) implants

Intervention

ECG-derived measures of cardiac repolarization (time-based, vectorcardiographic, and singular value decomposition derived measures) from 60 second 12-lead ECG recordings

Outcome

Occurrence of appropriate ICD therapyhard clinical

Advanced ECG measures of repolarization heterogeneity (TWR-rel and TCRT) independently predict the risk of appropriate therapy in patients with new ICD implants.

Discussion

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Implication

May refine arrhythmic risk stratification in new ICD recipients; hypothesis-generating, requiring prospective validation before clinical use.

Cite This Study

Shi et al. (2016) studied this question.

synapsesocial.com/papers/6a1e6efdd2dd52381c327fde https://doi.org/10.1111/anec.12390

Topics

Cardiac device therapy

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Implication

May refine arrhythmic risk stratification in new ICD recipients; hypothesis-generating, requiring prospective validation before clinical use.

Analysis of ECG Measures of Cardiac Repolarization in Relation to Arrhythmic Events in an Implantable Cardioverter Defibrillator Population

Structured PICO

Discussion

Implication

Cite This Study

Topics

Analysis of ECG Measures of Cardiac Repolarization in Relation to Arrhythmic Events in an Implantable Cardioverter Defibrillator Population

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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