March 7, 2009Circulation Arrhythmia and ElectrophysiologyOpen Access

Prediction of Ventricular Tachyarrhythmias by Intracardiac Repolarization Variability Analysis

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Why the study?

Does increased intracardiac QT variability predict VT/VF events in patients with structural heart disease and an ICD?

Population

298 patients with structural heart disease and an implanted Medtronic ICD for primary or secondary…

Design

Cohort

Follow-up

mean 16+/-8 months

Authors

LTLarisa G. TereshchenkoElectrophysiology BFBarry FeticsRobin Medical (United States)PDPeter P. DomitrovichCleveland Clinic

Discussion

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Implication

QTVI may aid VT/VF risk stratification in ICD patients; extends ECG data to intracardiac signals but remains hypothesis-generating.

Structured PICO

Does increased intracardiac QT variability predict VT/VF events in patients with structural heart disease and an ICD?

Population

298 patients with structural heart disease and an implanted Medtronic ICD for primary (n=231, 78%) or secondary (n=67, 22%) prevention of sudden cardiac death, mean age 59+/-14, 73% male.

Intervention

QT variability index (QTVI) assessment from surface ECG, far-field (FF), and near-field (NF) intracardiac electrograms (EGMs)

Outcome

Ventricular tachycardia/ventricular fibrillation (VT/VF) events and fast VT/VF (cycle length <=240 ms) receiving appropriate ICD therapieshard clinical

Increased intracardiac QT variability measured via ICD electrograms or surface ECG independently predicts ventricular tachyarrhythmias in patients with structural heart disease.

Cite This Study

Tereshchenko et al. (2009) studied this question.

synapsesocial.com/papers/6a73e17014e943abc869f818 https://doi.org/10.1161/circep.108.829440

Topics

Ventricular arrhythmias Cardiac device therapy

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Prediction of Ventricular Tachyarrhythmias by Intracardiac Repolarization Variability Analysis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Prediction of Ventricular Tachyarrhythmias by Intracardiac Repolarization Variability Analysis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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