Why the study?
How does spontaneous baroreflex sensitivity evolve during normal pregnancy?
Population
23 women with normal pregnancy without history of hypertension, mean age 27.4±4.4 years, at 12-14 weeks of…
Design
Cohort
Follow-up
up to 26-30 weeks of gestation
Authors
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Baroreflex sensitivity dynamics in normal pregnancy should not yet alter clinical monitoring; leaves open mechanistic links to orthostatic tolerance.
How does spontaneous baroreflex sensitivity evolve during normal pregnancy?
Spontaneous baroreflex sensitivity fluctuates during normal pregnancy, with early pregnancy showing normal or increased values that decrease during tilt, and late pregnancy showing decreased overall sensitivity alongside restored orthostatic tolerance.
Gugova et al. (2008) studied this question.
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