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January 1, 2019Therapeutic Advances in Respiratory DiseaseOpen Access

Extended anticoagulation after venous thromboembolism: should it be done?

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Key result

This review addresses the most recent data concerning extended anticoagulation in VTE secondary prophylaxis, balancing the reduction of VTE recurrence risk against the risk of bleeding.

Why the study?

VTE recurrence risk often persists beyond 6 months of anticoagulation, raising questions about whether bleeding risks outweigh the benefits of extended treatment and which patients require prolonged therapy.

Does extended anticoagulation reduce VTE recurrence without unacceptable bleeding risk in patients with venous thromboembolism?

Population

Patients suffering from VTE

Comparison

Extended anticoagulation for secondary prophylaxis

Design

Review

Authors

CFCaio Júlio César dos Santos FernandesDCDaniela CalderaroBPBruna Piloto

Discussion

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Member takes

Overview

Extended anticoagulation in VTE requires individualized bleeding-risk assessment; this review leaves open optimal duration and agent selection.

Structured PICO

Does extended anticoagulation reduce VTE recurrence without unacceptable bleeding risk in patients with venous thromboembolism?

P
Population
Patients with venous thromboembolism (VTE)
I
Intervention
Extended anticoagulation for secondary prophylaxis

This review evaluates the recent data on the efficacy and safety of extended anticoagulation for secondary prophylaxis in patients with venous thromboembolism.

Cite This Study

Fernandes et al. (2019) conducted a review in Venous thromboembolism (VTE). Extended anticoagulation was evaluated. This review addresses the most recent data concerning extended anticoagulation in VTE secondary prophylaxis, balancing the reduction of VTE recurrence risk against the risk of bleeding.

synapsesocial.com/papers/6a20949ce9ae715d2b0c8fa5https://doi.org/10.1177/1753466619878556
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