Key result
Transcatheter mitral valve intervention is an emerging treatment for mitral regurgitation that avoids the risks of open heart surgery, though challenges remain in developing adaptable devices.
Transcatheter mitral valve intervention is an emerging, less invasive alternative to open heart surgery for mitral regurgitation, though significant challenges remain in device development and achieving durable results.
May support less invasive mitral regurgitation treatment in high surgical risk patients; leaves open needs for adaptable devices and durable outcomes.
Mitral regurgitation (MR) is a valvular heart disease associated with significant morbidity and mortality. Transcatheter mitral valve intervention (TMVI) repairs or replaces the mitral valve through small arterial and venous entry sites and so avoids risks associated with open heart surgery. Transcatheter devices targeting components of the mitral apparatus are being developed to repair or replace it. Numerous challenges remain including developing more adaptable devices and correction of multiple components of the mitral annulus to attain durable results. The mitral valve apparatus is a complex structure and understanding of the mechanisms of MR is essential in the development of TMVI. There will likely be a complementary role between surgery and TMVI in the near future.
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Markham et al. (2018) conducted a review in Mitral regurgitation. Transcatheter mitral valve intervention (TMVI) was evaluated. Transcatheter mitral valve intervention is an emerging treatment for mitral regurgitation that avoids the risks of open heart surgery, though challenges remain in developing adaptable devices.
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