Key result
MitraClip (63%, 31/49) and surgical mitral valve repair (100%, 38/38) achieved ≤2+ MR at 12 months, with changes in left atrial strain depending on baseline LA and LV function.
Why the study?
Does MitraClip placement improve left atrial strain and strain rate compared to surgical mitral valve repair in patients with degenerative mitral regurgitation?
Population
87 subjects with degenerative mitral regurgitation enrolled in the randomized EVEREST II trial.
Comparison
MitraClip placement vs Surgical mitral valve repair
Design
RCT, Randomized (as part of the EVEREST II trial)
Follow-up
12 months
Authors
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LA strain changes after MitraClip or surgery depend on baseline LA/LV function, not procedure; extends evidence guiding expectations by pre-procedural status.
RCT (n=87)
randomized
Does MitraClip placement improve left atrial strain and strain rate compared to surgical mitral valve repair in patients with degenerative mitral regurgitation?
Changes in left atrial strain following MitraClip or surgical repair for degenerative mitral regurgitation are dependent on baseline left atrial and ventricular function rather than the specific intervention type.
İpek et al. (2018) conducted an RCT in Degenerative mitral regurgitation (n=87). MitraClip procedure vs. Surgical mitral valve repair was evaluated on Changes in left atrial (LA) strain and strain rate at 12 months. MitraClip (63%, 31/49) and surgical mitral valve repair (100%, 38/38) achieved ≤2+ MR at 12 months, with changes in left atrial strain depending on baseline LA and LV function.
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