Why the study?
Does achieving ≥95% platelet inhibition at 10 minutes with GP IIb/IIIa antagonists reduce the risk of MACEs in patients undergoing PCI?
Does achieving ≥95% platelet inhibition at 10 minutes with GP IIb/IIIa antagonists reduce the risk of MACEs in patients undergoing PCI?
Achieving ≥95% platelet inhibition at 10 minutes after GP IIb/IIIa antagonist initiation is an independent predictor of reduced MACE risk following PCI.
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May support early platelet monitoring in PCI; leaves open whether targeting ≥95% inhibition improves outcomes in trials.
Steinhubl et al. (2001) studied this question.
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