Key result
Female gender was associated with a nearly four-fold increased odds of masked uncontrolled hypertension (OR 3.93) compared to male gender among older treated hypertensive patients.
Cross-Sectional (n=273)
No
In older treated hypertensive patients, office BP measurements alone are insufficient to differentiate white-coat from uncontrolled hypertension or controlled from masked hypertension, highlighting the importance of ambulatory blood pressure monitoring.
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May prompt greater ABPM use in older treated women; leaves open prospective confirmation and outcome impact.
BACKGROUND: Hypertension is the main risk factor for cardiovascular diseases, affecting more than half the elderly population. It is essential to know if they have proper control of hypertension. The aim of this study was to identify the associated factors to masked uncontrolled hypertension and false uncontrolled hypertension in older patients. METHODS: Two-hundred seventy-three individuals (70.1 ± 6.7 years-old) had blood pressure (BP) measured at the office and by ambulatory BP monitoring (ABPM), with the definition of controlled group (C), individuals with high office BP and adequate ABPM, called white-coat effect group (WCE), uncontrolled (UC), and subjects with appropriate office BP and elevated ABPM denominated masked effect group (ME). Age, body mass index, diabetes, pulse pressure (PP) and BP dipping during sleep were evaluated (Kruskal-Wallis test and logistic regression models). Female gender was associated with a greater chance of being of ME group, which showed a higher PP and lower BP dipping during sleep. CONCLUSIONS: In older individuals, office BP measurements did not allow the detection of associated factors that would permit to differentiate WCE from UC group and C from ME group. ABPM favored the identification of a higher PP and a lower BP dipping during sleep in the masked effect and uncontrolled groups.
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Lima et al. (2016) conducted a cross-sectional in Hypertension (n=273). Female gender vs. Male gender was evaluated on Masked uncontrolled hypertension (masked effect) (OR 3.93, 95% CI 1.26-12.21, p=0.02). Female gender was associated with a nearly four-fold increased odds of masked uncontrolled hypertension (OR 3.93) compared to male gender among older treated hypertensive patients.
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