Why the study?
Does white-coat hypertension increase the risk of cardiovascular events compared to normal blood pressure in treated and untreated persons with isolated systolic hypertension?
Population
7,295 adults without a history of cardiovascular disease or diastolic hypertension, including 1,593 with…
Comparison
White-coat hypertension in treated and untreated… vs Normal blood pressure
Design
Cohort
Follow-up
median 10.6 years
Authors
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Treated white-coat hypertension signals higher risk; cohort data extend stratification but leave optimal management open.
Does white-coat hypertension increase the risk of cardiovascular events compared to normal blood pressure in treated and untreated persons with isolated systolic hypertension?
Untreated white-coat hypertension carries a similar cardiovascular risk to normal blood pressure, but treated patients with normalized ambulatory BP and residual white-coat effect remain at higher risk than untreated normotensives.
Franklin et al. (2012) studied this question.
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