December 1, 1997Neurology
Improving interobserver variation in reporting gadolinium-enhanced MRI lesions in multiple sclerosis
Why the study?
Does observer training improve interobserver agreement in reporting gadolinium-enhanced MRI lesions in multiple sclerosis?
Population
Scans of 16 multiple sclerosis patients evaluated by five inexperienced and five experienced observers
Comparison
Observer training and consensus formation vs Before training (baseline performance)
Design
Other
Authors
Discussion
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Member takes
Implication
Training may boost MS MRI reporting consistency; leaves open effects on trial endpoints or practice.
Structured PICO
Does observer training improve interobserver agreement in reporting gadolinium-enhanced MRI lesions in multiple sclerosis?
P
Population
Scans of 16 multiple sclerosis patients evaluated by five inexperienced and five experienced observers
I
Intervention
Observer training and consensus formation
C
Comparator
Before training (baseline performance)
O
Outcome
Interobserver agreement (weighted kappa values and mean average difference to the median scores) in reporting baseline, new, and persistent gadolinium-enhanced lesionssurrogate
Observer training improves interobserver agreement in reporting gadolinium-enhanced MRI lesions in MS, validating its use as an outcome parameter in clinical trials.
Cite This Study
Barkhof et al. (1997) studied this question.