Improve the Prevention of Sudden Cardiac Arrest in Patients With Post-Acute Myocardial Infarction

Figures

• 

  Figure 1. Study Cohort Flow Chart Points at which patients were exited or continued through the study are shown along with a breakdown of when patients met referral criteria and were referred for sudden cardiac death (SCD) risk stratification and management as well as when patients met implantable cardioverter-defibrillator (ICD)/cardiac resynchronization therapy–defibrillator (CRT-D) implant criteria and were implanted with a device. “Lost to follow-up” means the patients were not able to be followed up any longer due to lost contact with the patient. “Missed visit” means that a patient continued in the study but missed a specific visit. “Missed patients were exited” means that a patient missed the last visit of the study and was therefore exited at that timepoint because there were no more visits to complete after that. ∗Single patient could meet referral criteria for SCD risk stratification and management at multiple visits. †Single patient could be referred for SCD risk stratification and management at multiple visits. ‡2 patients were recorded as having completed SCD risk stratification and management visits but not as having been referred. §1 patient was recorded as having met…

• 

  Figure 2. Patient Referral, Device Indication, and Implant (A) The percentage of patients that met referral criteria at any point during the study are shown overall and in each geographical region. The error bars represent the 95% CI. Overall 26.7%, Mainland China 19.0%, India subcontinent (ISC) 31.1%, South Korea 20.3%, Taiwan 16.7%, Middle East, Africa, Central Asia, Turkey (MEACAT) 43.1%, and South East Asia (SEA) 31.6%. (B) Of the 398 patients who met further SCD risk stratification and management criteria, the percent referred for SCD risk stratification and management is shown overall and by geography. (C) Of the 224 patients who had an SCD risk stratification and management visit, the percent who met an ICD/CRT-D indication is shown overall and by geography. Overall 56.7%, Mainland China 41.9%, ISC 71.6%, South Korea 43.8%, Taiwan 46.2%, MEACAT 60.0%, and SEA 66.7%. (D) Of the 127 patients who met ICD/CRT-D referral criteria, the percentage of ICD/CRT-D implants in each geographical region are shown: Overall 14.2%, Mainland China 34.6%, ISC 2.1%, South Korea 57.1%, Taiwan 16.7%, MEACAT 8.3%, and SEA 0.0%. Abbreviations as in Figure 1.

• 

  Figure 3. Incidence of Device Implant Over Time The incidence of device implant is shown over time (A) overall and (B) for each geographical region. Abbreviations as in Figure 2.

• 

  Figure 4. Mortality in Post-MI Patients by Geography The percentage of sudden cardiac death (blue) and non-sudden cardiac death (red) mortality are shown overall and by geography during the study period. Abbreviations as in Figure 2.

• 

  Central Illustration. Patient Movement Through the Post–Myocardial Infarction Care Pathway Of the total patients who met referral criteria for further sudden cardiac death (SCD) risk stratification and management, the percent of patients that continued in the care path (blue), appropriately exited the care path (gray) or exited the care path while still at risk of SCD (red) are shown at each step of the care pathway. CRT-D = cardiac resynchronization therapy–defibrillator; ICD = implantable cardioverter-defibrillator.