Key result
Early orthotopic heart transplantation for irreversible anthracycline cardiotoxicity in a child with advanced lymphoma involves significant medical and ethical complexities.
This case report highlights the medical and ethical considerations of performing an orthotopic heart transplant in a child with severe anthracycline-induced cardiotoxicity and a history of advanced lymphoma.
Requires multidisciplinary ethical review for such transplants; case-level data leaves management questions open for future research.
A child with advanced stage large cell lymphoma in remission developed overwhelming, irreversible anthracycline cardiac toxicity incompatible with life early in her treatment course. The medical complexities and ethical issues concerning a decision to proceed with orthotopic heart transplantation are discussed.
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Morgan et al. (2002) studied this question. Early orthotopic heart transplantation for irreversible anthracycline cardiotoxicity in a child with advanced lymphoma involves significant medical and ethical complexities.
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