Population
Bovine cardiac myosin and its papain subfragment-1
Comparison
Steady-state and pre-steady-state kinetic… vs Published values for rabbit skeletal-muscle…
Design
Preclinical
Authors
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Caution against clinical extrapolation from rabbit data; extends comparative myosin kinetics research but leaves translation open.
Cardiac myosin has slower isomerization rate constants than skeletal muscle myosin, which may relate to the functional properties of different muscle types.
Taylor et al. (1976) studied this question.
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