Why the study?
Does coronary artery stenosis result in more severe myocardial perfusion abnormalities during exercise in dogs with left ventricular hypertrophy compared to normal dogs?
Does coronary artery stenosis result in more severe myocardial perfusion abnormalities during exercise in dogs with left ventricular hypertrophy compared to normal dogs?
Left ventricular hypertrophy secondary to long-term pressure overload increases vulnerability to myocardial hypoperfusion during exercise in the presence of coronary artery stenosis.
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LVH may heighten hypoperfusion risk with stenosis in this model; leaves open translation to human exercise ischemia.
Bache et al. (1990) studied this question.
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