Key result
Childhood metabolic syndrome was associated with higher arterial pulse wave velocity in adulthood after 21 years (P<0.007), while recovery from the syndrome resulted in lower PWV (P<0.001).
Why the study?
Does childhood metabolic syndrome and recovery from it affect arterial pulse wave velocity in adulthood?
Cohort (n=945)
Does childhood metabolic syndrome and recovery from it affect arterial pulse wave velocity in adulthood?
p-value: p=<0.007
Childhood metabolic syndrome predicts increased arterial stiffness in adulthood, but recovery from the syndrome is associated with decreased arterial stiffness, highlighting the importance of early risk factor control.
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May support targeting childhood metabolic syndrome to limit adult arterial stiffness; extends longitudinal data but leaves causality open.
Koivistoinen et al. (2011) conducted a cohort in Metabolic syndrome (n=945). Childhood metabolic syndrome vs. No childhood metabolic syndrome was evaluated on Arterial pulse wave velocity (PWV) (p=<0.007). Childhood metabolic syndrome was associated with higher arterial pulse wave velocity in adulthood after 21 years (P<0.007), while recovery from the syndrome resulted in lower PWV (P<0.001).
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