Key result
Lithium discontinuation completely resolves severe sinus bradycardia and syncope induced by chronic toxicity.
Why the study?
Lithium is primarily known for neurological and renal side effects, while cardiac side effects are rarely reported.
Population
An 80-year-old woman with chronic lithium toxicity
Design
Case report
Authors
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May warrant checking lithium levels in unexplained bradycardia; leaves open optimal monitoring strategies in elderly patients.
Case Report (n=1)
Chronic lithium toxicity can present with severe cardiac manifestations such as sinus node dysfunction and bradycardia, which resolve upon discontinuation of the drug.
Heidari et al. (2025) conducted a case report in Chronic lithium toxicity (n=1). Lithium was evaluated on Cardiac manifestations (severe sinus bradycardia). Chronic lithium toxicity in an 80-year-old woman caused severe sinus bradycardia and loss of consciousness, which resolved completely following the discontinuation of lithium.
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