Why the study?
Does mental stress induce coronary and peripheral vasomotor responses that correlate with endothelial function in patients undergoing coronary angiography?
Population
38 patients aged 59±8 years undergoing coronary angiography
Comparison
Mental stress induced by mental arithmetic… vs Rest/baseline
Design
Cross-sectional
Key result
Mental stress-induced coronary blood flow responses correlated with endothelium-dependent coronary microvascular function (r=0.38, P=0.03) and peripheral microvascular circulation (r=-0.60, P=0.004).
Authors
Loading...
Mental stress responses may reflect endothelial microvascular dysfunction; hypothesis-generating for peripheral surrogates pending prospective validation.
Cross-Sectional (n=38)
Does mental stress induce coronary and peripheral vasomotor responses that correlate with endothelial function in patients undergoing coronary angiography?
Coronary microvascular responses to mental stress are determined by endothelium-dependent function and are reflected in the peripheral microvascular circulation.
Effect estimate: r = 0.38
p-value: p=0.03
Hammadah et al. (2018) conducted a cross-sectional in Patients undergoing coronary angiography (n=38). Mental stress vs. Rest was evaluated on Correlation between mental stress-induced coronary blood flow response and endothelium-dependent CBF changes with acetylcholine (r = 0.38, p=0.03). Mental stress-induced coronary blood flow responses correlated with endothelium-dependent coronary microvascular function (r=0.38, P=0.03) and peripheral microvascular circulation (r=-0.60, P=0.004).