Population
Poliovirus virions and infected cells
Design
Preclinical
Authors
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Supports poliovirus encapsidation specificity; leaves open mechanistic and therapeutic extensions beyond animal models.
A new ribonuclease protection method demonstrates that poliovirus encapsidation is highly specific for positive strands, which are present in massive excess over negative strands.
Novak et al. (1991) studied this question.
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