Key result
Diabetes linked to ~17% higher PWV versus healthy volunteers via cuff oscillometry and toe photoplethysmography.
Why the study?
The authors sought to develop a method to measure pulse wave velocity along the entire body simultaneously with standard blood pressure measurement.
Does a novel method using a tonometer cuff and toe PPG sensor effectively measure pulse wave velocity differences between healthy volunteers and patients with diabetes mellitus?
Cross-Sectional (n=29)
Does a novel method using a tonometer cuff and toe PPG sensor effectively measure pulse wave velocity differences between healthy volunteers and patients with diabetes mellitus?
Absolute Event Rate: 5.905% vs 5.055%
p-value: p=<0.001
A novel method using a standard tonometer cuff and toe PPG sensor can rapidly measure pulse wave velocity and detect increased vascular stiffness in patients with diabetes.
In this paper, we propose a method for measuring a pulse wave velocity (PWV) along the entire body of the patient with the use of a standard tonometer cuff and a photoplethysmography (PPG) sensor attached to a toe. This approach makes it possible to calculate PWV simultaneously with the measurement of a blood pressure (BP), which takes several minutes. To test the developed method, 2 contrasting groups of subjects were recruited: group 1 (n=15) - healthy volunteers; group 2 (n=14) - patients with diabetes mellitus (DM). Healthy volunteers had the lowest median PWV value: 5.055 [4.427; 5.295] m/s, whereas in the group 2, the median PWV was significantly higher than in the group 1: 5.905 [5.612; 6.215] m/s, p<0.001. The proposed method for measuring PWV correlates with clinical data and allows a rapid integral assessment of vascular stiffness in both the trunk and lower extremities.
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Lapitan et al. (2023) conducted a cross-sectional in Diabetes mellitus (n=29). Diabetes mellitus vs. Healthy volunteers was evaluated on Pulse wave velocity (PWV) (p=<0.001). Pulse wave velocity measured via cuff oscillometry and toe photoplethysmography was significantly higher in patients with diabetes mellitus than healthy volunteers (5.905 vs 5.055 m/s; p<0.001).
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