Key result
Adequate blood pressure control over 5 years significantly reduced left ventricular mass index from 138 to 112 g/m2 (p<0.05), whereas untreated hypertension led to progressive hypertrophy.
Why the study?
Does adequate blood pressure control reverse left ventricular hypertrophy and alter geometry patterns in hypertensive patients?
Population
100 hypertensive patients older than 18 years
Comparison
Regular effective antihypertensive treatment… vs No regular medication, or regular treatment not…
Design
Cohort
Follow-up
5 years
Authors
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May support LVH regression via BP control in hypertension; leaves open geometry effects on outcomes.
Observational (n=100)
No
Does adequate blood pressure control reverse left ventricular hypertrophy and alter geometry patterns in hypertensive patients?
Absolute Event Rate: 112% vs 164%
p-value: p=<0.05
Adequate blood pressure control is necessary to reverse left ventricular hypertrophy in hypertensive patients, though left ventricular geometry patterns remain largely stable over time.
Conrady et al. (2005) conducted an observational in Essential hypertension (n=100). Adequate blood pressure control vs. Poorly controlled or untreated hypertension was evaluated on Left ventricular mass index (LVMI) at 5 years (p=<0.05). Adequate blood pressure control over 5 years significantly reduced left ventricular mass index from 138 to 112 g/m2 (p<0.05), whereas untreated hypertension led to progressive hypertrophy.
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