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Hypothesis-generating from level 5 data; leaves open need for prospective validation before clinical consideration.
2 Markle Scholar in Academic Medicine, Department of Medicine, Medical College of Virginia, Richmond, Virginia. 3 Department of Pathology, University of North Carolina, School of Medicine. 4 Department of Medicine, Duke University Medical Center, Durham, North Carolina.
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Harlan et al. (1966) studied this question.
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