Key result
Left atrial tumor resection yields ~85% 15-year survival with no significant sex-based differences.
Why the study?
Cardiac tumors predominantly occur in females, but how outcomes differ between men and women required examination.
Are there gender-related differences in outcomes and satisfaction following surgical resection of left atrial tumors?
Cohort (n=80)
No
Are there gender-related differences in outcomes and satisfaction following surgical resection of left atrial tumors?
Surgical resection of left atrial tumors yields excellent early and long-term outcomes with high patient satisfaction, which are consistent across both genders despite higher baseline operative risk scores in women.
Answers are grounded in this paper and cite their sources.
Supports resection despite higher female risk scores; leaves open need for prospective gender-stratified validation.
Background: Cardiac tumors are rare, with a low incidence of between 0.0017 and 0.19%. The majority of cardiac tumors are benign and predominantly occur in females. The aim of our study was to examine how outcomes differ between men and women. Methods: From 2015 to 2022, 80 patients diagnosed with suspected myxoma were operated on. In all patients, preoperative, perioperative, and postoperative data were recorded. Such patients were identified and included in a retrospective analysis focused on gender-related differences. Results: Patients were predominantly female (n = 64; 80%). The mean age was 62.76 ± 13.42 years in female patients and 59.65 ± 15.84 years in male patients (p = 0.438). The body mass index (BMI) was comparable in both groups: between 27.36 ± 6.16 in male and 27.09 ± 5.75 (p = 0.945) in female patients. Logistic EuroSCORE (LogES) (female: 5.89 ± 4.6; male: 3.95 ± 3.06; p = 0.017) and EuroSCORE II (ES II) (female: 2.07 ± 2.1; male: 0.94 ± 0.45; p = 0.043), both scores to predict the mortality in cardiac surgery, were significantly higher in female patients. Two patients died early, within 30 days after surgery: one male and one female patient. Late mortality was defined as the 5-year survival rate, which was 94.8%, and 15-year survival rate, which was 85.3% in our cohort. Causes of death were not related to the primary tumor operation. The follow up showed that satisfaction with surgery and long-term outcome was high. Conclusion: Predominately female patients presented with left atrial tumors over a 17-year period. Relevant gender differences aside from that were not evident. Surgery could be performed with excellent early (within 30 days after surgery) and late results (follow up after discharge).
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Sido et al. (2023) conducted a cohort in Left atrial tumors (suspected myxoma) (n=80). Female sex vs. Male sex was evaluated on Gender-related differences in early and late surgical outcomes. Surgical resection of left atrial tumors resulted in excellent early and long-term outcomes with no significant gender-related differences despite women having higher baseline surgical risk scores.
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