Oropharyngeal squamous cell carcinoma (OSCC) has been recognized as an immunosuppressive disease. Various mechanisms have been proposed for immune escape, including dysregulation of immune checkpoints such as the programmed cell death 1:programmed cell death-ligand 1 (PD-L1) pathway. We investigated the expression of PD-L1 in human papillomavirus (HPV)-negative and HPV-positive OSCC to determine its prevalence and prognostic relevance.
No takes yet. Share an insight, caveat, or question.
Kim et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: