Key result
A diagnostic model including pericardial ADA, lymphocyte/neutrophil ratio, peripheral leukocyte count and HIV status achieved 96% sensitivity and 97% specificity for tuberculous pericarditis.
Why the study?
What are the most accurate diagnostic tests and models for tuberculous pericarditis in patients with pericardial effusions?
Population
233 consecutive patients presenting with pericardial effusions
Design
Cohort
Authors
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Supports high-accuracy diagnostic model for tuberculous pericarditis; leaves open prospective validation before clinical adoption.
Observational (n=233)
What are the most accurate diagnostic tests and models for tuberculous pericarditis in patients with pericardial effusions?
Pericardial fluid IFN-gamma is a highly accurate diagnostic test for tuberculous pericarditis, and a clinical model incorporating ADA provides a robust alternative.
Reuter et al. (2006) conducted an observational in tuberculous pericarditis (n=233). Diagnostic model including pericardial ADA, lymphocyte/neutrophil ratio, peripheral leukocyte count and HIV status was evaluated on Diagnosis of tuberculous pericarditis. A diagnostic model including pericardial ADA, lymphocyte/neutrophil ratio, peripheral leukocyte count and HIV status achieved 96% sensitivity and 97% specificity for tuberculous pericarditis.
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