Key result
Lung allograft recipients exhibited a 30% reduction in maximal expiratory pressure and a 39% decrease in ankle dorsiflexor strength compared to matched controls (p<0.05).
Why the study?
Do stable lung allograft recipients have reduced respiratory and limb muscle function compared to age- and sex-matched controls?
Population
9 clinically stable lung allograft recipients with reduced exercise capacity
Design
Case-control
Authors
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Expiratory and limb weakness may limit exercise capacity in stable lung recipients; hypothesis-generating for prospective intervention trials.
Case-Control (n=9)
Do stable lung allograft recipients have reduced respiratory and limb muscle function compared to age- and sex-matched controls?
p-value: p=<0.05
Stable lung allograft recipients experience expiratory and lower limb weakness that may contribute to their reduced exercise capacity despite normal resting pulmonary and hemodynamic function.
PANTOJA et al. (1999) conducted a case-control in Lung allograft recipients with reduced exercise capacity (n=9). Lung allograft recipient status vs. Age- and sex-matched control subjects was evaluated on Respiratory muscle strength (MIP and MEP) and ankle dorsiflexor muscle strength (MVC) (p=<0.05). Lung allograft recipients exhibited a 30% reduction in maximal expiratory pressure and a 39% decrease in ankle dorsiflexor strength compared to matched controls (p<0.05).
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