Why the study?
Does the disruption of neural pathways between the lungs and the central nervous system in heart-lung transplant recipients alter the pattern of breathing during exercise compared to heart transplant recipients?
Population
14 patients: 7 recipients of heart-lung transplants with normal pulmonary function and 7 recipients of heart…
Comparison
Heart-lung transplantation vs Heart transplantation
Design
Cross-sectional
Authors
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Suggests intrapulmonary receptors shape exercise ventilation; hypothesis-generating and should not yet change practice.
Does the disruption of neural pathways between the lungs and the central nervous system in heart-lung transplant recipients alter the pattern of breathing during exercise compared to heart transplant recipients?
Heart-lung transplant recipients exhibit an altered breathing pattern during exercise characterized by a disproportionate increase in tidal volume at a reduced respiratory rate, suggesting intrapulmonary receptors regulate the pattern of ventilation.
Sciurba et al. (1988) studied this question.