Key result
Heart transplant patients had an altered response to upright exercise compared to controls, including a higher steady-state heart rate (108 vs 96 beats/min, p<0.05) and lower stroke index.
Why the study?
Does upright bicycle exercise elicit different hemodynamic and metabolic responses in heart transplant patients compared to controls?
Population
11 patients who have undergone cardiac transplantation and 12 controls (total n=23)
Comparison
Upright bicycle exercise vs 12 controls performing the same upright bicycle…
Design
Cross-sectional
Authors
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May inform exercise test interpretation in heart transplant recipients; leaves open prognostic impact and protocol needs.
Case-Control (n=23)
Does upright bicycle exercise elicit different hemodynamic and metabolic responses in heart transplant patients compared to controls?
Absolute Event Rate: 108% vs 96%
p-value: p=<0.05
Heart transplant patients demonstrate an altered, less efficient hemodynamic and metabolic response to upright exercise compared to controls.
Martin et al. (1994) conducted a case-control in Cardiac transplantation (n=23). Cardiac transplantation vs. Controls was evaluated on Steady-state heart rate during upright bicycle exercise (beats/min) (p=<0.05). Heart transplant patients had an altered response to upright exercise compared to controls, including a higher steady-state heart rate (108 vs 96 beats/min, p<0.05) and lower stroke index.
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