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December 1, 2001Pediatric Transplantation

Cardiorespiratory functional assessment after pediatric heart transplantation

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Why the study?

Does pediatric heart transplantation alter cardiorespiratory responses to exercise compared to healthy matched controls?

Population

14 consecutive pediatric heart transplant recipients and 14 healthy matched controls.

Comparison

Bruce treadmill test and lung function tests vs Healthy matched controls

Design

Case-control

Authors

EPEnrica PastoreATAttilio TurchettaLALeonello Attias

Discussion

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Overview

Pediatric transplant recipients show impaired exercise responses; hypothesis-generating for rehabilitation trials before practice change.

Structured PICO

Does pediatric heart transplantation alter cardiorespiratory responses to exercise compared to healthy matched controls?

P
Population
14 consecutive pediatric heart transplant recipients (6 girls, 8 boys, age range 5-15 years) and 14 healthy matched controls.
I
Intervention
Bruce treadmill test and lung function tests (FVC, FEV1)
C
Comparator
Healthy matched controls
O
Outcome
Cardiorespiratory responses to exercise including duration of test, resting and maximum heart rates, maximum systolic blood pressure, peak oxygen consumption (VO2 peak), and cardiac outputsurrogate

Pediatric heart transplant recipients exhibit reduced exercise tolerance and chronotropic incompetence compared to healthy controls, highlighting the need for supervised physical activity programs.

Cite This Study

Pastore et al. (2001) studied this question.

synapsesocial.com/papers/6a7574dc99129e9915f58e1bhttps://doi.org/10.1034/j.1399-3046.2001.t01-2-00032.x
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiopulmonary Exercise Testing in Children Following Surgery for Tetralogy of Fallot1991 · 24 citations
  2. 2The Pediatric Cardiac Rehabilitation Program at Childrenʼs Hospital National Medical Center, Washington, DC1987 · 4 citations
  3. 3Cardiorespiratory responses to exercise training after orthotopic cardiac transplantation.1988 · 283 citations