What question did this study set out to answer?

The study aims to quantify exercise capacity in cardiac transplanted patients and identify predictive factors for improved outcomes.

November 1, 1997European Heart JournalOpen Access

Predictive factors of maximal aerobic capacity after cardiac transplantation

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Population

85 cardiac transplanted patients, mean age 52.1 +/- 11.8 years

Design

Cross-sectional

Follow-up

1 to 100 months after transplantation

Authors

HDH DouardHôpital Cardiologique du Haut-Lévêque EPE. ParrensCabinet Office MBMarc‐Alain BillesHôpital Cardiologique du Haut-Lévêque

Discussion

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Implication

Chronotropic reserve may limit post-transplant exercise capacity; hypothesis-generating for targeted interventions pending prospective trials.

Key Points

The study aims to quantify exercise capacity in cardiac transplanted patients and identify predictive factors for improved outcomes.
Eighty-five cardiac transplanted patients underwent exercise testing with gas exchange measurements.
Assessments were conducted 1 to 100 months post-transplantation.
Univariate and multiple regression analyses were performed to determine correlations.
Mean peak VO2 was 21.1 +/- 6 ml.min-1.kg-1, with significant correlation to chronotropic reserve (r = 0.63; P < 0.001).
Chronotropic reserve, time from transplantation, age of donor, and age of patient were the best predictors of peak VO2.
The study confirms a persistent decrease in aerobic capacity despite cardiac transplantation.

Structured PICO

Population

85 cardiac transplanted patients, mean age 52.1 +/- 11.8 years

Outcome

Maximal aerobic capacity (peak VO2) and its predictive factorssurrogate

Aerobic functional capacity remains decreased after cardiac transplantation and is primarily limited by chronotropic reserve, patient age, donor age, and time from transplantation.

Cite This Study

Douard et al. (1997) studied this question.

synapsesocial.com/papers/6a1d0185e19a8dd1302f1efa https://doi.org/10.1093/oxfordjournals.eurheartj.a015178

Topics

Heart transplantation

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Implication

Chronotropic reserve may limit post-transplant exercise capacity; hypothesis-generating for targeted interventions pending prospective trials.

Predictive factors of maximal aerobic capacity after cardiac transplantation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Predictive factors of maximal aerobic capacity after cardiac transplantation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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