Key result
A novel noninvasive imaging method using low rank and sparse constraints outperformed existing Tikhonov regularization and L1-norm methods in accurately locating ectopic pacing sites in 39 PVC cases.
Why the study?
The authors explored using low rank and sparse constraints for the noninvasive estimation of epicardial and endocardial potentials from body-surface electrocardiographic data to locate premature ventricular contraction foci.
Does a low rank and sparse constraint model improve the accuracy of noninvasive estimation of cardiac potentials and localization of PVC foci compared to existing regularization methods?
Does a low rank and sparse constraint model improve the accuracy of noninvasive estimation of cardiac potentials and localization of PVC foci compared to existing regularization methods?
A novel low rank and sparse constraint model improves the noninvasive localization of premature ventricular contraction foci from body-surface ECG data.
Should not yet alter PVC localization practice; leaves open prospective validation of low-rank sparse ECG imaging.
In this study, we explore the use of low rank and sparse constraints for the noninvasive estimation of epicardial and endocardial extracellular potentials from body-surface electrocardiographic data to locate the focus of premature ventricular contractions (PVCs). The proposed strategy formulates the dynamic spatiotemporal distribution of cardiac potentials by means of low rank and sparse decomposition, where the low rank term represents the smooth background and the anomalous potentials are extracted in the sparse matrix. Compared to the most previous potential-based approaches, the proposed low rank and sparse constraints are batch spatiotemporal constraints that capture the underlying relationship of dynamic potentials. The resulting optimization problem is solved using alternating direction method of multipliers. Three sets of simulation experiments with eight different ventricular pacing sites demonstrate that the proposed model outperforms the existing Tikhonov regularization (zero-order, second-order) and L1-norm based method at accurately reconstructing the potentials and locating the ventricular pacing sites. Experiments on a total of 39 cases of real PVC data also validate the ability of the proposed method to correctly locate ectopic pacing sites.
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Fang et al. (2019) studied Premature ventricular contractions (PVCs) (n=39). Low rank and sparse constraints for noninvasive estimation of cardiac potentials vs. Tikhonov regularization (zero-order, second-order) and L1-norm based method was evaluated on Accurately reconstructing the potentials and locating the ventricular pacing sites. A novel noninvasive imaging method using low rank and sparse constraints outperformed existing Tikhonov regularization and L1-norm methods in accurately locating ectopic pacing sites in 39 PVC cases.
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