Key result
In patients with essential hypertension, maximum carotid intima-media thickness was positively correlated with asymptomatic periventricular hyperintensity (ρ = 0.558), indicating a relationship between carotid atherosclerosis and cerebral lesions.
Why the study?
Are carotid structural and hemodynamic parameters associated with asymptomatic white and gray matter lesions in patients with essential hypertension?
Population
49 hospitalized patients with essential hypertension, mean age 58.7, 27 male / 22 female, in Japan. Key…
Design
Cross-sectional, MRI interpreted in a manner blinded with respect to the…
Authors
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Carotid atherosclerosis may mark cerebral lesion risk in essential hypertension; leaves open causal role and need for longitudinal studies.
Cross-Sectional (n=49)
Single-blind
No
Are carotid structural and hemodynamic parameters associated with asymptomatic white and gray matter lesions in patients with essential hypertension?
Effect estimate: ρ = 0.558
p-value: p=0.0001
In patients with essential hypertension, increased carotid intima-media thickness and decreased relative diastolic blood flow velocity are associated with asymptomatic cerebral white and gray matter lesions.
Kurata et al. (2005) conducted a cross-sectional in Essential hypertension (n=49). Carotid intima-media thickness and hemodynamics was evaluated on Correlation between maximum carotid intima-media thickness (max IMT) and periventricular hyperintensity (PVH) (ρ = 0.558, p=0.0001). In patients with essential hypertension, maximum carotid intima-media thickness was positively correlated with asymptomatic periventricular hyperintensity (ρ = 0.558), indicating a relationship between carotid atherosclerosis and cerebral lesions.
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