A minimal resting time of 25 min is needed before measuring stabilized blood pressure in subjects addressed for vascular investigations

Figures

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  Figure 1. Evolution of the blood pressure and heart rate during the resting time. Evolution of measured systolic (red) and diastolic (blue) arterial blood pressure with time, expressed as mean and + /−1.96 standard deviation. Also shown, in black, is the evolution of heart rate over the measurement period (slightly displaced not to overlap the diastolic pressure); the scale for the cardiac frequency is given as the axis on the right hand side of the figure.

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  Figure 2. Evolution of systolic blood pressure with resting time stratified by treatment. Evolution of systolic blood pressure with resting time stratified by treatment. Left: patients receiving no chronic treatment; middle: patients receiving a treatment other than hypertensive drugs; right: patients receiving an hypertensive treatment (defined as receiving at least one drug from the following therapeutic classes: Diuretics, Betablockers or Angiotensin-converting-enzyme inhibitors).

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  Figure 3. Individual model fits for 12 randomly chosen patients in the study, according to the final model. Dots represent observations and the lines are the model predictions corresponding to the empirical Bayes estimates for each subject (individual predictions).

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  Figure 4. Predicted proportion of subjects diagnosed as hypertensive (systolic blood pressure above 140 mmHg) versus time of measurement. Left: single time, right: mean of 2 measurements (guidelines: 3 or 5 mn +1 or 2 mn). To obtain these figures, 1000 simulations of the original dataset were performed.