Key result
In patients with ST-segment elevation myocardial infarction treated with primary PCI, higher peak strain dispersion was independently associated with an increased risk of left ventricular remodeling at 6 months (OR 1.05).
Why the study?
LV remodeling is associated with higher heart failure hospitalization rates after STEMI, prompting investigation into the predictive value of peak strain dispersion for remodeling.
Does peak strain dispersion predict left ventricular remodeling in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention?
Population
76 STEMI patients undergoing primary PCI
Comparison
Patients with LV remodeling vs those without LV remodeling
Design
Prospective cohort study
Follow-up
6 months
Authors
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May enhance post-STEMI remodeling risk stratification after primary PCI; hypothesis-generating and requires prospective validation before clinical use.
Cohort (n=76)
No
Does peak strain dispersion predict left ventricular remodeling in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention?
Odds Ratio: 1.05 (95% CI 1.02–1.1)
p-value: p=<0.01
Peak strain dispersion measured by echocardiography within 48 hours of admission provides incremental value in predicting left ventricular remodeling at 6 months in patients with STEMI treated with primary PCI.
Wang et al. (2022) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=76). Peak strain dispersion (PSD) vs. Lower peak strain dispersion was evaluated on Left ventricular remodeling (increase in LVEDV ≥ 20% at 6 months) (OR 1.05, 95% CI 1.02-1.10, p=<0.01). In patients with ST-segment elevation myocardial infarction treated with primary PCI, higher peak strain dispersion was independently associated with an increased risk of left ventricular remodeling at 6 months (OR 1.05).
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