Why the study?
Does propranolol alter regional myocardial blood flow in an anaesthetized dog model of acute ischaemia?
Population
anaesthetized dog model of acute ischaemia
Design
Preclinical
Authors
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Does not reduce ischemic myocardial flow; hypothesis-generating for regional effects in human ischemia.
Does propranolol alter regional myocardial blood flow in an anaesthetized dog model of acute ischaemia?
In a canine model of acute ischemia, propranolol selectively decreases blood flow to non-ischemic myocardium without reducing flow to ischemic areas.
Pitt et al. (1970) studied this question.
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