Key result
High risk for Type 2 diabetes was associated with significantly lower heart rate variability (RMSSD) and a higher LF/HF ratio compared to low risk (P<0.005), indicating early cardiac autonomic dysfunction.
Why the study?
Reduced heart rate variability in T2DM patients leads to cardiac autonomic neuropathy and increased risk of sudden cardiac death, and identifying high-risk individuals may help prevent or delay complications.
Does an increased risk of Type 2 Diabetes Mellitus correlate with reduced heart rate variability in adults aged 40-55?
Cross-Sectional (n=60)
No
Does an increased risk of Type 2 Diabetes Mellitus correlate with reduced heart rate variability in adults aged 40-55?
p-value: p=<0.005
Higher risk for developing Type 2 diabetes is associated with reduced heart rate variability and altered sympathovagal balance, suggesting early cardiac autonomic dysfunction even before clinical diabetes onset.
May indicate early autonomic changes in high diabetes risk; leaves open prospective validation before clinical adoption.
Background: T2DM patients' cardiac autonomic function is different. Heart rate variability is diminished (HRV). Reduced HRV causes cardiac autonomic neuropathy and increased risk of SCD. Identifying high-risk T2DM patients can help avoid or postpone T2DM consequences. The Diabetes Risk Score questionnaire was created to analyze the patients. Aim: To study studied HRV in persons with different T2DM risk. Methods: Physiology Department conducted this experiment. It is a cross-sectional study involving 60 Patients. The RDS questionnaire will be completed by all participants. The RDS score puts them into Groups A, B, and C. 5 min short-term HRV will be measured in all three groups. The data were analysed using SPSS 23.0. ANOVA was used to compare the groups statistically. The variables were connected using the Pearson correlation test. Results: The post hoc (Dunn's) test demonstrated that HRV levels were considerably lower in high and moderate risk groups compared to mild risk groups. Conclusion: HRV levels declined with increased diabetes risk, showing a negative connection.
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Mahmood et al. (2022) conducted a cross-sectional in Risk of Type 2 Diabetes Mellitus (n=60). High risk for Type 2 Diabetes (Diabetes Risk Score) vs. Low risk for Type 2 Diabetes was evaluated on Heart rate variability (HRV) parameters including RMSSD and LF/HF ratio (p=<0.005). High risk for Type 2 diabetes was associated with significantly lower heart rate variability (RMSSD) and a higher LF/HF ratio compared to low risk (P<0.005), indicating early cardiac autonomic dysfunction.
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