What question did this study set out to answer?

This study investigates if anticoagulants can prevent acute coronary occlusion during early warning signs.

October 1, 1951HeartOpen Access

The Prevention of Impending Cardiac Infarction by Anticoagulant Treatment

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Why the study?

Does the administration of heparin or dicoumarol prevent acute coronary occlusion in patients with premonitory symptoms?

Population

Patients with premonitory/prodromal symptoms of acute coronary occlusion (impending cardiac infarction)

Comparison

Heparin, dicoumarol, or both vs Patients in whom treatment failed, and patients…

Design

Case_series

Authors

KSKenneth SmithSt. Jude Children's Research Hospital CPC. PappRoyal London Hospital

Discussion

Member takes

Implication

Does not support practice change from case reports alone; leaves open the role of anticoagulants in prodromal symptoms.

Key Points

This study investigates if anticoagulants can prevent acute coronary occlusion during early warning signs.
Examine effects of heparin and dicoumarol in preventing cardiac infarction during premonitory symptoms.
Review animal experiments and clinical work alongside treated patients.
Contrast outcomes with a comparable group that did not receive treatment.
Anticoagulant treatment was effective in a group of patients, preventing acute coronary occlusion.
A contrast group showed a higher occurrence of cardiac infarction despite having premonitory symptoms.
Unusual cases where patients displayed prodromal symptoms without progressing to infarction were noted.

Structured PICO

Does the administration of heparin or dicoumarol prevent acute coronary occlusion in patients with premonitory symptoms?

Population

Patients with premonitory/prodromal symptoms of acute coronary occlusion (impending cardiac infarction)

Intervention

Heparin, dicoumarol, or both

Comparator

Patients in whom treatment failed, and patients receiving no anticoagulant treatment

Outcome

Prevention of acute coronary occlusion (cardiac infarction)hard clinical

This early study examines the potential of using anticoagulants like heparin and dicoumarol to prevent impending myocardial infarction in patients presenting with prodromal symptoms.

Cite This Study

Smith et al. (1951) studied this question.

synapsesocial.com/papers/6a20d960dc4e16663149cc76 https://doi.org/10.1136/hrt.13.4.467

Topics

Anticoagulation in AF

View Full Paper

Ask AI

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The Prevention of Impending Cardiac Infarction by Anticoagulant Treatment

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

The Prevention of Impending Cardiac Infarction by Anticoagulant Treatment

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider