Age <75 years was associated with significantly higher survival compared to age ≥75 years in AMICS patients treated with a standard shock protocol (75.6% vs 50%; adjusted OR 10.4, P=0.001).
Cohort (n=300)
Yes
Odds Ratio: 10.4
Absolute Event Rate: 75.6% vs 50%
p-value: p=0.001
BACKGROUND: Acute myocardial infarction complicated by cardiogenic shock (AMICS) is associated with high mortality. Patients ≥75 years old represent an increasing proportion of those who present with AMICS and are at high risk for adverse outcomes. METHODS: The National Cardiogenic Shock Initiative includes patients with AMICS treated using a standard shock protocol with early invasive hemodynamic monitoring, mechanical circulatory support (MCS), and percutaneous coronary intervention (PCI). We evaluated the outcomes of patients based on their age group, dividing them into 1 vasopressor). CONCLUSIONS: Age is inversely proportional to survival; patients <75 years old have high rates of survival if treated using best practices with invasive hemodynamic monitoring, early MCS, and PCI. However, using a standardized protocol can improve survival in the elderly; therefore, age on its own should not be a reason to withhold PCI or MCS use.
Lemor et al. (Wed,) conducted a cohort in Acute myocardial infarction complicated by cardiogenic shock (AMICS) (n=300). Age <75 years vs. Age ≥75 years was evaluated on Survival (adjusted OR 10.4, p=0.001). Age <75 years was associated with significantly higher survival compared to age ≥75 years in AMICS patients treated with a standard shock protocol (75.6% vs 50%; adjusted OR 10.4, P=0.001).