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February 17, 2021Critical Pathways in Cardiology A Journal of Evidence-Based Medicine

Age <75 years was associated with significantly higher survival compared to age ≥75 years in AMICS patients treated with a standard shock protocol (75.6% vs 50%; adjusted OR 10.4, P=0.001).

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Why the study?

AMICS is associated with high mortality, and patients aged 75 years or older represent an increasing proportion at high risk for adverse outcomes.

Population

300 consecutive AMICS patients treated using a standard shock protocol

Comparison

Patients <75 years old vs ≥75 years old

Design

Registry-based cohort study

Key result

Age <75 years was associated with significantly higher survival compared to age ≥75 years in AMICS patients treated with a standard shock protocol (75.6% vs 50%; adjusted OR 10.4, P=0.001).

Authors

ALAlejandro LemorMBMir B. BasirSGSarah Gorgis

Discussion

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Overview

Supports age-stratified prognosis in AMICS; extends RCT evidence on elderly mortality despite standardized shock protocols.

Study Design

Type

Cohort (n=300)

Multicenter

Yes

PICO

P
Population
300 consecutive patients with acute myocardial infarction complicated by cardiogenic shock treated with a standard shock protocol, evaluated by age group.
E
Exposure / Comparator
Age <75 years vs Age ≥75 years
O
Primary Outcome
Survival — adjusted OR 10.4, p=0.001

Main Result

Odds Ratio: 10.4

Absolute Event Rate: 75.6% vs 50%

p-value: p=0.001

Cite This Study

Lemor et al. (2021) conducted a cohort in Acute myocardial infarction complicated by cardiogenic shock (AMICS) (n=300). Age <75 years vs. Age ≥75 years was evaluated on Survival (adjusted OR 10.4, p=0.001). Age <75 years was associated with significantly higher survival compared to age ≥75 years in AMICS patients treated with a standard shock protocol (75.6% vs 50%; adjusted OR 10.4, P=0.001).

synapsesocial.com/papers/6a20d9946c1dfe058b17febchttps://doi.org/10.1097/hpc.0000000000000255
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