Key result
Second-generation cryoballoon ablation for persistent AF resulted in a 29.7% recurrence rate at 37 months, with left atrial area >21 cm2 and AF history >2 years independently predicting recurrence.
Why the study?
Does second-generation cryoballoon ablation prevent arrhythmia recurrence in patients with persistent atrial fibrillation?
Population
101 patients with persistent atrial fibrillation
Design
Cohort
Follow-up
median 37 months
Authors
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Supports cryoballoon ablation for persistent AF in selected patients; leaves open randomized comparisons to other modalities.
Observational (n=101)
No
Does second-generation cryoballoon ablation prevent arrhythmia recurrence in patients with persistent atrial fibrillation?
Second-generation cryoballoon ablation maintains sinus rhythm at 3 years in approximately 70% of patients with persistent AF, with best outcomes in those with nonenlarged left atria and short AF history.
Akkaya et al. (2017) conducted an observational in Persistent atrial fibrillation (n=101). Second-generation cryoballoon ablation was evaluated on First documented recurrence (> 30 seconds) of AF, atrial flutter, or atrial tachycardia after a 3-month blanking period. Second-generation cryoballoon ablation for persistent AF resulted in a 29.7% recurrence rate at 37 months, with left atrial area >21 cm2 and AF history >2 years independently predicting recurrence.
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