Key result
The Arctic Front Advance cryoballoon achieved 100% (10/10) full pulmonary vein isolation compared to 60% (6/10) with the first-generation Arctic Front balloon in a canine model.
Why the study?
Does the second-generation Arctic Front Advance cryoballoon improve pulmonary vein isolation compared to the first-generation Arctic Front balloon in a canine model?
Population
20 pulmonary veins from 10 healthy dogs weighing 29.8 ± 1.1 kg
Comparison
Ablation with the second-generation Arctic Front… vs Ablation with the first-generation Arctic Front…
Design
Preclinical
Follow-up
30 days
Authors
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Second-generation cryoballoon improves PVI in canines; leaves open clinical translation to human AF ablation.
Does the second-generation Arctic Front Advance cryoballoon improve pulmonary vein isolation compared to the first-generation Arctic Front balloon in a canine model?
Absolute Event Rate: 100% vs 60%
The second-generation Arctic Front Advance cryoballoon demonstrated improved pulmonary vein isolation and lesion completeness compared to the first-generation device in a canine model.
Coulombe et al. (2013) studied Pulmonary vein isolation (healthy dogs) (n=10). Arctic Front Advance (AFA) cryoballoon vs. Arctic Front (AF) cryoballoon was evaluated on Full pulmonary vein isolation. The Arctic Front Advance cryoballoon achieved 100% (10/10) full pulmonary vein isolation compared to 60% (6/10) with the first-generation Arctic Front balloon in a canine model.