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January 11, 2018European Journal of Cardio-Thoracic SurgeryOpen Access

Reimplantation versus remodelling with ring annuloplasty: comparison of mid-term outcomes after valve-sparing aortic root replacement†

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Key result

Root remodelling with extra-aortic ring annuloplasty yielded similar 5-year survival free from aortic insufficiency ≥2 or reoperation compared to reimplantation (84% vs 83%; P=0.62).

Why the study?

Does root remodelling with extra-aortic ring annuloplasty improve mid-term outcomes compared to reimplantation in patients undergoing valve-sparing aortic root replacement?

Population

142 patients undergoing valve-sparing aortic root replacement at the Montreal Heart Institute

Comparison

Root remodelling with extra-aortic ring… vs Reimplantation technique

Design

Cohort

Follow-up

mean 3.9 years

Authors

MLMarien LenoirCentre Hospitalier Universitaire Sainte-JustineBMBart MaesenCardiac SurgeryLSLouis‐Mathieu StevensCentre Hospitalier de l’Université de Montréal

Discussion

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Implication

Similar mid-term durability supports root remodelling with annuloplasty as an alternative; leaves open randomized confirmation in valve-sparing aortic root replacement.

Study Design

Type

Cohort (n=142)

Multicenter

No

Structured PICO

Does root remodelling with extra-aortic ring annuloplasty improve mid-term outcomes compared to reimplantation in patients undergoing valve-sparing aortic root replacement?

P
Population
142 patients undergoing valve-sparing aortic root replacement via remodelling with extra-aortic annuloplasty or reimplantation, followed for a mean of 3.9 years.
E
Exposure
Root remodelling with extra-aortic ring annuloplasty
C
Comparator
Reimplantation technique
O
Outcome
Mid-term outcomes including overall survival, freedom from aortic valve reoperation, and survival free from aortic insufficiency ≥2 or reoperation at 5 yearshard clinical

Main Result

Absolute Event Rate: 84% vs 83%

p-value: p=0.62

Mid-term outcomes after root remodelling with extra-aortic annuloplasty are comparable to reimplantation, demonstrating its effectiveness in stabilizing annular dimensions.

Cite This Study

Lenoir et al. (2018) conducted a cohort in Valve-sparing aortic root replacement (n=142). Root remodelling with extra-aortic ring annuloplasty vs. Reimplantation technique was evaluated on 5-year survival free from aortic insufficiency ≥2 or reoperation (p=0.62). Root remodelling with extra-aortic ring annuloplasty yielded similar 5-year survival free from aortic insufficiency ≥2 or reoperation compared to reimplantation (84% vs 83%; P=0.62).

synapsesocial.com/papers/6a20e0c5dc4e16663149d232https://doi.org/10.1093/ejcts/ezy016
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 12017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines2017 · 2,532 citations
  2. 22017 ESC/EACTS Guidelines for the management of valvular heart disease2017 · 642 citations
  3. 3The combined role of sinuses of Valsalva and flow pulsatility improves energy loss of the aortic valve2015 · 41 citations