March 1, 2008Current Opinion in Cardiology
Transcatheter aortic valve implantation: time to expand?
Key result
Transcatheter aortic valve implantation is a promising technique for elderly, high-risk patients with severe aortic stenosis, though no randomized clinical trials have been reported so far.
Why the study?
Does transcatheter aortic valve implantation provide a safe and effective alternative to conventional surgery in elderly and higher-risk patients with severe aortic stenosis?
Population
Elderly and higher-risk patients suffering severe, symptomatic aortic stenosis
Comparison
Transcatheter aortic valve implantation via… vs Conventional surgery
Design
Review
Authors
Discussion
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Implication
TAVI may be considered in select high-risk elderly patients with severe AS; leaves open the need for randomized trials to establish safety and efficacy.
Structured PICO
Does transcatheter aortic valve implantation provide a safe and effective alternative to conventional surgery in elderly and higher-risk patients with severe aortic stenosis?
P
Population
Elderly and higher-risk patients suffering severe, symptomatic aortic stenosis
I
Intervention
Transcatheter aortic valve implantation (TAVI) via transfemoral or transapical approach
C
Comparator
Conventional surgery
TAVI is emerging as a promising clinical reality for high-risk patients with severe aortic stenosis, though randomized trial data is still pending.
Limitations
- Current clinical studies are of prospective design with observational character
- No prospectively randomized clinical trials have been reported so far
- No prospectively randomized clinical trials reported so far
Cite This Study
Walther et al. (2008) conducted a review in Severe, symptomatic aortic stenosis. Transcatheter aortic valve implantation vs. Conventional surgery was evaluated. Transcatheter aortic valve implantation is a promising technique for elderly, high-risk patients with severe aortic stenosis, though no randomized clinical trials have been reported so far.