Why the study?
Does pulmonary vein isolation using the second-generation cryoballoon improve 1-year stable sinus rhythm in patients with atrial fibrillation?
Population
2,363 patients with atrial fibrillation (paroxysmal and persistent) pooled from 15 studies
Comparison
Pulmonary vein isolation using the… vs 'Bonus' strategy (in subgroup analysis)
Design
Meta-analysis
Follow-up
1 year
Key result
Pulmonary vein isolation using the second-generation cryoballoon achieved an overall 1-year clinical success rate of 81% in patients with atrial fibrillation.
Authors
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Supports second-generation cryoballoon PVI for AF rhythm control; confirms high 1-year success in large pooled analysis.
Meta-Analysis (n=2,363)
Does pulmonary vein isolation using the second-generation cryoballoon improve 1-year stable sinus rhythm in patients with atrial fibrillation?
Pulmonary vein isolation using the second-generation cryoballoon is highly effective for treating atrial fibrillation, with an 81% 1-year clinical success rate and comparable efficacy between 'no-bonus' and 'bonus' ablation strategies.
He et al. (2015) conducted a meta-analysis in Atrial fibrillation (AF) (n=2,363). Pulmonary vein isolation using the second-generation cryoballoon (CB-2G) was evaluated on 1-year clinical success rate. Pulmonary vein isolation using the second-generation cryoballoon achieved an overall 1-year clinical success rate of 81% in patients with atrial fibrillation.