Key result
Combined atherosclerotic lesions in diabetes are highly prevalent and demand aggressive therapy to curb progression.
Highlights the high prevalence and clinical importance of combined atherosclerotic vascular lesions in patients with diabetes mellitus, advocating for aggressive screening and management.
Supports multifocal atherosclerosis screening in diabetes; leaves open whether aggressive therapy improves outcomes.
During latest decade, as threat of acute complications of diabetes mellitus was surmounted, cardiovascular complications became leadingcause of death. Clinical manifestation of coronary, brachiocephalic and renal atherosclerosis is quite dramatic in diabetes mellitus,which determines extent of dissemination and intensity of lesions. Combination of these mutually confounding conditions is a characteristicproblem of patients with diabetes mellitus. Presence of 2+ risk factors (one of which is diabetes mellitus in itself) requiresactive examination in order to rule out coronary, brachiocephalic, peripheral and renal artery lesions. Aggressive care is necessaryin order to control progression of disease and administer adequate conservative and endovascular treatment with account of high riskof combination of lesions.
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Gracheva et al. (2012) conducted a review in Diabetes mellitus. Combined atherosclerotic lesions in patients with diabetes mellitus are highly prevalent and require active examination and aggressive therapy to control disease progression.
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