Key result
Diabetes remains linked to ~4-fold higher cardiovascular mortality, requiring multifactorial CAD management.
Why the study?
Persons with diabetes remain up to four-times as likely to die of cardiovascular disease despite recent reductions in coronary artery disease and cardiovascular events, necessitating individualized multifactorial treatment approaches.
A contemporary review highlighting that management of coronary artery disease in patients with Type 2 diabetes requires individualized, multifactorial medicinal and procedural treatments.
Answers are grounded in this paper and cite their sources.
Supports multifactorial CAD care in diabetes; leaves open optimal individualized regimens for prospective study.
Diabetes mellitus is a metabolic disease with microvascular and macrovascular complications, and is well known to increase the risk of coronary atherosclerosis. Despite recent reductions in the prevalence of coronary artery disease and cardiovascular events in the USA, persons with diabetes remain up to four-times as likely to die of cardiovascular disease than the general population. Diabetes is associated with an atherogenic lipid profile, induces a hypercoagulable state, and increases coronary plaque volume, progression and instability. Medicinal and procedural treatments in the patient with diabetes should be multifactorial, targeting and managing the many coexisting risk factors that contribute to atherosclerosis. This type of treatment is complex and should be individualized, and guided by a careful review of recent literature. Here we discuss important clinical data and their impact on up-to-date recommendations for the management of coronary artery disease in the patient with Type 2 diabetes mellitus.
No takes yet. Share an insight, caveat, or question.
Raymond et al. (2013) conducted a review in Type 2 diabetes mellitus and coronary artery disease. Medicinal and procedural treatments was evaluated. Persons with diabetes remain up to four-times as likely to die of cardiovascular disease than the general population, requiring multifactorial and individualized management of coronary artery disease.
Synapse has enriched 10 related papers. Consider them for comparative context: