What question did this study set out to answer?

This research aims to evaluate the clinical outcomes in patients with isolated one-vessel coronary disease.

February 1, 1983CirculationOpen Access

Outcome in one-vessel coronary artery disease.

View Full Paper

Ask AI

Bookmark

Why the study?

Does surgical therapy improve survival or reduce cardiac events compared to nonsurgical therapy in patients with one-vessel coronary artery disease?

Population

688 patients with isolated stenosis of one major coronary artery (one-vessel coronary artery disease)

Comparison

Surgical therapy vs Nonsurgical therapy

Design

Cohort

Follow-up

5 years

Authors

RCRobert M. CaliffInterventional Cardiology YTY Tomabechi KLKerry L LeeDuke University

Discussion

Member takes

Implication

Supports initial nonsurgical management given high survival; leaves open need for RCTs to confirm equivalence in one-vessel disease.

Key Points

This research aims to evaluate the clinical outcomes in patients with isolated one-vessel coronary disease.
Analyzed outcomes in 688 patients with isolated stenosis of one major coronary artery.
Compared survival rates among patients with disease in the right coronary artery, left anterior descending artery, and left circumflex artery.
Assessed the relationship between left ventricular ejection fraction and survival over a 5-year period.
Survival rates exceeded 90% at 5 years for all anatomic subgroups.
Patients with proximal lesions on the LAD had decreased survival compared to those with distal lesions.
No significant differences in survival or cardiac event rates were found between surgical and nonsurgical therapies.

Structured PICO

Does surgical therapy improve survival or reduce cardiac events compared to nonsurgical therapy in patients with one-vessel coronary artery disease?

Population

688 patients with isolated stenosis of one major coronary artery (one-vessel coronary artery disease)

Intervention

Surgical therapy

Comparator

Nonsurgical therapy

Outcome

Survival rate and total ischemic events (death and nonfatal infarction)hard clinical

Patients with one-vessel coronary artery disease have an excellent 5-year survival rate (>90%), and while surgical therapy provides superior angina relief, it does not improve survival or reduce total cardiac events compared to nonsurgical therapy.

Cite This Study

Califf et al. (1983) studied this question.

synapsesocial.com/papers/6a20e98adc4e16663149d8a2 https://doi.org/10.1161/01.cir.67.2.283

View Full Paper

Ask AI

Bookmark

Outcome in one-vessel coronary artery disease.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Outcome in one-vessel coronary artery disease.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider