Key result
Among survivors of ischaemic stroke at a young age, 34% had a total maximum carotid intima-media thickness ≥1.5 mm after a mean follow-up of 11.9 years.
Why the study?
Is carotid intima-media thickness increased and associated with vascular morbidity in young survivors of ischemic stroke?
Cross-Sectional (n=140)
Is carotid intima-media thickness increased and associated with vascular morbidity in young survivors of ischemic stroke?
Carotid intima-media thickness is frequently increased in young survivors of ischemic stroke and correlates with traditional cardiovascular risk factors and recurrent vascular events.
CIMT elevation signals higher vascular risk in young stroke survivors; leaves open whether CIMT-guided interventions improve outcomes.
BACKGROUND AND PURPOSE: Previous studies have shown significantly higher mortality and vascular morbidity amongst patients with ischaemic stroke onset at a young age compared with controls after a mean observation time of more than 11 years. METHODS: In the present cross-sectional study, we measured the carotid intima-media thickness (IMT) in 140 (75%) of 187 survivors of ischaemic stroke after a mean observation time of 11.9 years. Their mean age when included was 41.1 years. IMT was measured by B-mode ultrasonography. RESULTS: Total maximum IMT <1.0 mm was found in 34 (24%) patients, [1.0-1.2 mm) in 29 (21%) patients, [1.2-1.5 mm) in 29 (21%) patients and >or=1.5 mm in 48 (34%) patients. Increasing total maximum IMT was related to increasing age, male gender, recurrent ischaemic stroke, coronary atherosclerosis, peripheral atherosclerosis, smoking, hypertension and diabetes mellitus. DISCUSSION: IMT changes confirm increased vascular morbidity in patients who suffered ischaemic stroke at a young age.
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Waje‐Andreassen et al. (2008) conducted a cross-sectional in Ischaemic stroke at a young age (n=140). Ischaemic stroke at a young age was evaluated on Carotid intima-media thickness (IMT). Among survivors of ischaemic stroke at a young age, 34% had a total maximum carotid intima-media thickness ≥1.5 mm after a mean follow-up of 11.9 years.
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